Many research have been targeted on the selective separation of hydrogen chloride (HCl) fuel, however its seize and conversion in situ continues to be at a standstill. Herein, a pioneering try and make use of deep eutectic solvent (DES) because the “courier” to mix HCl seize and in situ conversion was introduced. Impressively, the best HCl absorption capability is set to be 3.95 mol/mol, or 0.672 g/g, or 18.4 mol/kg at 1.0 bar and 30 C in binary DES primarily based on EmimCl/Im. The inner transmission mechanism between imidazole and HCl was revealed by DFT–primarily based theoretical calculation. The response between HCl and epoxides achieved 99 % conversion underneath delicate circumstances within the absence of solvent, making the complete response ecologically benign. Water extraction was used to recycle the DES from the response system, and it maintained good catalytic efficiency after ten cycles. The exhaust HCl–SO2 combined gases from the sucralose business was additional investigated, which proves the opportunity of selective conversion of HCl. Moreover, a believable response–separation–integration (RSI) technique was proposed to keep away from the excessive vitality consumption of desorption, which offers a novel perception into future purposes. It’s believed that the great outcomes, mixed with its simplicity of operation and the excessive recyclability of the catalyst, make this inexperienced technique environmentally pleasant and cost-effective. This work reveals an efficient strategy for the coupling of HCl seize and conversion underneath delicate circumstances.