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Wednesday, March 29, 2023

Physics – Reminiscence of Blood Cells

• Physics 16, s4

Researchers have studied how irregularly formed particles journey by microchannels. Their work may have relevance to the transport of pink blood cells by capillaries.

Z. Shen/College of Bordeaux

Blood flowing by arteries obeys easy fluid-dynamical equations. However from these massive vessels department progressively smaller ones, and within the tiniest vessels of all—capillaries, that are barely bigger than pink blood cells—the fluid equations are not legitimate. To acquire a greater description of blood move in such vessels, Chaouqi Misbah of Grenoble Alpes College in France and his colleagues numerically analyzed a system of particles touring by a community of microchannels [1]. They discovered that the pace at which the particles unfold by the lattice is ruled by the particles’ focus and deformability.

The researchers modeled a honeycomb lattice by which irregularly formed, deformable particles traveled from prime to backside. When a particle encountered a fork, it may “select” both the best or left channel. In a typical fluid—one wherein the particles are very small relative to the channel width—the selection a particle makes is random and unbiased of its earlier decisions. This “random stroll” causes the fluid to diffuse laterally because it strikes by the community. However Misbah and his colleagues discovered that at low concentrations, irregularly formed, stiff particles had a robust reminiscence: if a particle selected the left fork beforehand, it strongly most popular to decide on left once more. Consequently, a fluid of such particles exhibited “superdiffusion,” spreading laterally a lot quicker than within the random-walk case. If the researchers made the particles squishy, the reminiscence impact wasn’t as sturdy, however the fluid nonetheless expanded outward quicker than typical.

Misbah thinks that the position that particles’ stiffness and form play on particle transport may have implications for illnesses that have an effect on pink blood cells, comparable to sickle cell anemia and malaria.

–Katie McCormick

Katie McCormick is a contract science author based mostly in Sacramento, California.


  1. Z. Shen et al., “Anomalous diffusion of deformable particles in a honeycomb community,” Phys. Rev. Lett. 130, 014001 (2023).

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Organic PhysicsFluid Dynamics

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